The drugs we reach for without thinking – ibuprofen, naproxen, even everyday-dose aspirin – are far from harmless when used long term. By blocking prostaglandins, they ease pain but also strip away the stomach’s natural protection, opening the door to ulcers, internal bleeding and, in severe cases, death. Dr. Mark Porter warns that NSAIDs are behind around a third of all adverse drug reaction admissions in the NHS, filling one in five hospital beds.

The danger climbs steeply for people over 65, anyone with a history of ulcers, indigestion, heartburn, heart failure, kidney disease, or those already on blood thinners such as warfarin, apixaban, or low‑dose aspirin. Even “occasional” tablets can worsen symptoms; regular use can be catastrophic. The message is stark: never assume over‑the‑counter means safe. Weigh every dose, talk to your doctor, and treat these everyday pills with the same caution you’d give any powerful drug.